File:A-Reaction-Diffusion-Model-of-ROS-Induced-ROS-Release-in-a-Mitochondrial-Network-pcbi.1000657.s004.ogv

Summary

Description
English: Image sequence illustrating the effect of 10–20µM KO2 on ΔΨm (upper) and ROS (lower). Guinea-pig ventricular myocyte was loaded with TMRM and CM-DCF and then partially permeabilized with 25µg/ml saponin as described in methods. Image frames were collected every 3.5 seconds using a two-photon laser scanning fluorescence microscope. Note localized oscillations in mitochondrial ΔΨm.
Date
Source Video S1 from Zhou L, Aon M, Almas T, Cortassa S, Winslow R, O'Rourke B (2010). "A Reaction-Diffusion Model of ROS-Induced ROS Release in a Mitochondrial Network". PLOS Computational Biology. DOI:10.1371/journal.pcbi.1000657. PMID 20126535. PMC: 2813265.
Author Zhou L, Aon M, Almas T, Cortassa S, Winslow R, O'Rourke B
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Category:Videos of experimental biophysical methods Category:Videos of heart failure Category:Videos of myocardial infarction Category:Cellular pathology Category:Molecular pathology Category:Integrative physiology Category:Videos of computer simulations Category:Cavia porcellus anatomy Category:Mitochondrial membrane potentials Category:Multiphoton fluorescence microscopy Category:Videos of mitochondria Category:Biological models Category:Cardiac myocytes Category:Reactive oxygen species Category:Videos of signal transduction Category:Superoxides Category:Media from PLOS Computational Biology Category:Uploaded with Open Access Media Importer Category:Videos from open-access scholarly articles Category:Uploaded with Open Access Media Importer and needing category review Category:Videos of laser-induced fluorescence Category:Ogv videos Category:Video display resolution 324 x 120
Category:Biological models Category:CC-BY-2.5 Category:Cardiac myocytes Category:Cavia porcellus anatomy Category:Cellular pathology Category:Integrative physiology Category:Media from PLOS Computational Biology Category:Mitochondrial membrane potentials Category:Molecular pathology Category:Multiphoton fluorescence microscopy Category:Ogv videos Category:Reactive oxygen species Category:Superoxides Category:Uploaded with Open Access Media Importer Category:Uploaded with Open Access Media Importer and needing category review Category:Video display resolution 324 x 120 Category:Videos from open-access scholarly articles Category:Videos of computer simulations Category:Videos of experimental biophysical methods Category:Videos of heart failure Category:Videos of laser-induced fluorescence Category:Videos of mitochondria Category:Videos of myocardial infarction Category:Videos of signal transduction