File:FAS Choline.jpg

Uploaded by KShaw KKowalec
Upload date 2011-02-18T06:44:56Z
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Summary

Description The nutriepigenetic pathway of maternal choline-deficient diets helps to elucidate the development of fetal alcohol syndrome. Pregnant rodents fed diets low in choline were found to give rise to offspring with diminished neurological capacity. This is similar to pregnant rodents whom were fed ethanol and were found to have alterations in the metabolism of 1-carbon compounds. This leads to diminished levels of methyl donors available for methylating DNA; thus allowing for overexpression of normally silenced genes causing neurological defects in their offspring.
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Author KShaw KKowalec

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Category:CC-BY-SA-3.0 Category:Fetal alcohol syndrome Category:GFDL Category:Genetics files (fine-grained classification needed) Category:License migration redundant Category:Nutrition Category:Self-published work