File:MiRNA Regulation of DNA Damage Response.svg
| Uploaded by | Ariutta |
|---|---|
| Upload date | 2019-06-19T18:44:17Z |
| MIME type | image/svg+xml |
| Dimensions | 1904 × 918 px |
| File size | 277.6 KB |
Summary
| Description |
English: This is the first out of two pathways which deals with the DNA damage response. It is comprised of two central gene products (ATM and ATR) influenced by different sources of DNA damage (in blue). The two central genes can both be divides into their most important genes. For the ATM pathway these are TP53 and CHEK2, while CHEK1 is most important for the ATR pathway.
The goal of this first pathway is to provide an overview of the most important gene products, processes and changes in cell condition elicited by the DNA damage response while keeping it clear and understandable. Also some microRNAs are implemented to visualize the possible effects they can induce. By doing so a better understanding of the role microRNA play in the DNA damage response might arise. All processes take place in the cytoplasm, except when mentioned differently. |
| Date | |
| Source |
https://www.wikipathways.org/index.php/Pathway:WP1530  Source materials for this file are available from Commons Archive: |
| Author | Jan Krumeich, Stan Gaj, Egon Willighagen, Kristina Hanspers, Martina Kutmon, Alexander Pico, Andra Waagmeester, Martijn van Iersel, Ryan Miller, Susan Coort, zahra roudbari |
Licensing
 
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This file is made available under the Creative Commons CC0 1.0 Universal Public Domain Dedication. |
| The person who associated a work with this deed has dedicated the work to the public domain by waiving all of their rights to the work worldwide under copyright law, including all related and neighboring rights, to the extent allowed by law. You can copy, modify, distribute and perform the work, even for commercial purposes, all without asking permission.
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| Annotations | This image is annotated: View the annotations at Commons |
